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SURMOUNT-1 (NEJM 2022) tested tirzepatide a dual GIP/GLP-1 receptor agonist in 2,539 adults with obesity and achieved up to 20.9% mean weight loss at the highest dose. 57% of participants
Interplay of Chronic Kidney Disease and the Effects of Tirzepatide in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity: The SUMMIT Trial - ScienceDirect
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